Science, properly understood, is a methodology by which one can come to an understanding of objects and actions that are sensible (in the philosophical sense, that is, can be sensed). It has nothing, pro or con, to say about anything that is only intelligible (in the philosophical sense -- meaning perceivable by the mind alone). It is also descriptive rather than prescriptive -- that is, it will explain how to achieve a goal but can not, in itself, offer guidance as to what that goal should be.
To make the claim that materialism is somehow more real than another system because science has revealed nothing that isn't sensible in the philosophical sense is an error and derives from a misapprehension of what science does and how it does it.
One can mask (though not remove) one's error by labelling any questions that are either unanswerable in one's framework or assertions that there are needs not met by one's chosen model as irrational, based on fairy tales, or a misunderstanding of one's position. The holes still exist.
Radical Materialism, like any other faith-based position that lays claim to undisputed superiority in describing all of reality, ends up doing violence to reality since it has no choice but to eliminate what does not suit it. Those who insist on such positions are no different in kind from any other religious fundamentalist, and certainly have no greater claim to rationality.
The ultimate error is, in the final analysis, not in being materialist, atheist, monotheist, pantheist, or whatever, but in adopting the position that there is a single system that has all the answers (or even all the so-called 'relevant' answers).


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