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Photographs, the old author's annotations (as long as it's not a high-school copy of the Lord of the Flies with central themes underlined, highlighted, etc.).
I have to say, the most interesting thing I have ever found in a second hand book is a very long letter from an unidentified woman to her best friend/female lover?. It rambles from tangent to tangent and finishes off with, "I'm sorry this is in pencil, but I am not allowed sharp objects right now." It makes me wonder and is such an intrusion into other people's private lives...
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(EW. And occasionally, I find people's food-y fingerprints on the pages XP. Which I can't deny doing myself, but other people's bolognese sauce on p.54 of Mother Night doesn't do it for me.)