The first line, of course, is:
Of man's first disobedience, and the fruit...
How would you scan this first line? Obviously its not straight iambic pentametre, especially given the extra syllable at the end.
I scan it as:
U** / *** /** /U*/*U*U***U**U***/
Of man's first disobedience, and the fruit
Obviously "disobedience" is the ringer in this sentence - is there any special way in which the reader's of the 17th century would have stressed this word differently?
What purpose does Milton have starting a blank verse epic with such a strangely metered line?